In recent years, increased rates of HPV infection and anal cancer among men have encouraged the medical community to search for causes and ways to identify the less insidious precursor, anal intraepithelial neoplasia. Risk factors for the development of anal cancer have been identified and should be discussed with patients—especially those infected with human immunodeficiency virus—who have a much higher than normal risk of anal cancer. The Alliance has been instrumental in creating guidelines for anal Pap testing and encouraging other medical professionals and clinics to do the same, and these guidelines are provided herein. Sign In.
Abnormal Anal Pap Smear, Dysplasia & Anal Cancer
Abnormal Anal Pap Smear, Dysplasia & Anal Cancer - Colon & Rectal Surgery Associates
Sarah M. Bean, David C. Anal cancer screening programs are gaining momentum within the United States and Europe. The goal of such programs is to detect and eradicate human papillomavirus HPV related intraepithelial lesions of the anal canal before progression to invasive squamous cell carcinoma occurs. Programs are designed to screen the anal-rectal transformation zone of a highly selected group of at-risk patients using exfoliative cytology techniques, comparable to the cervical Pap test. Patients with abnormal cytology results should be referred for anoscopy, during which the anal-rectal mucosa will be carefully visually inspected by a qualified physician. Abnormal areas are biopsied for definitive histological diagnosis, and treatment should be offered as appropriate.
Anal Pap smears: Should we be doing them?
Sarah M. Bean, David C. Anal cancer screening programs are gaining momentum within the United States and Europe.
See Screening for Anal Cancer for more information about the different screening methods. A digital anal-rectal examination DARE by a clinician may detect small lumps in the anal canal, which can indicate the early signs of anal cancer. However, more complex screening methods used to look for anal cancer are anal Pap smears and high resolution anoscopy.